Browsing: Toxicology

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Toxicology

TCA Overdoses and Mimics: Don’t Delay, Don’t Be Led Astray

8/10/2022 Lance Shaull, MD , Andrew Mittelman, MD
At toxic doses, tricyclic antidepressants (TCAs) cause blockade of sodium channels, muscarinic receptors, and alpha-adrenergic receptors. Slowed ventricular contraction, tachycardia, and vasodilation
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Cardiology , Toxicology

Torsades de Pointes after Olanzapine Use for Agitation

4/10/2022 Joshua Hall, DO , Nauman Rashid
Second-generation antipsychotics are becoming more commonly used because of their safety profiles. Nevertheless, this case demonstrates a risk of QTc prolongation and torsades de pointes with olanzapi
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Social EM , Toxicology

Coastal Harmful Algal Blooms and Climate Change – Toxic Challenges for Emergency Medicine

4/10/2022 Catharina Giudice, MD , Caitlin S Rublee, MD, MPH , Priya Srihari, MD
Climate health and public health are linked in ways that become more obvious every year. In this context, we will summarize the marine toxins that are sending more patients to the emergency department
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Toxicology

Bupropion Toxicity

4/10/2022 E. Mason Jackson, MD , Erik Fisher, MD, FACEP
Initially marketed as an atypical antidepressant for adults, bupropion gained popularity for its use in tobacco cessation and for its lack of sexual side effects commonly seen with other typical antid
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Toxicology , COVID-19

The Toxicology of COVID

4/10/2022 Michael Keenan, MD , Vincent Calleo, MD
Emergency physicians have watched with excitement the rapid development of COVID-19 vaccines. However, while we were watching the rapid scientific development, there was a concurrent wave of misguided
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Toxicology

Fomepizole for Acetaminophen Toxicity: A Novel Use for a Classic Antidote

12/12/2021 Shelby Randall, DO , Nicholas Titelbaum, MD , Alexa Peterson, DO, MS , Katelynn Baska, DO , Nicole Ovregaard, MPH, CPH
Acetaminophen toxicity is one of the most common causes of liver toxicity in the United States. New data reveals that fomepizole may be hepatoprotective in high dose acetaminophen toxicity when review
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Hematology , Pain Management , Toxicology

A Real Pain in the Mouth: Acquired Methemoglobinemia

12/12/2021 Emily Wolery, MD , Cynthia Oliva, MD , K.T. Dyer, MD
Acquired methemoglobinemia, a pathologic condition due to elevated quantities of methemoglobin in the blood, is an infrequent presentation in a healthy adult patient. This case illustrates the risk as
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Toxicology

Case of Doxepin Overdose

10/7/2021 Massud Atta, MD , Sanam Patel, MD , Jon Shivdat, DO , Pete Stueve, DO
Doxepin is a tricyclic antidepressant (TCA) that was primarily approved for depression but has also been approved by the Food and Drug Administration (FDA) to treat insomnia and anxiety. Do you know h
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Toxicology , Dermatology

Drug-Induced Erythema Multiforme

10/7/2021 Amna M. Farshori, DO , Daniel J. Schroder, DO
Erythema multiforme is an acute skin disorder. While most cases are the result of an infection, the condition can also result from autoimmune disorders, malignancy, and drug use.
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EMS , Disaster Medicine , Toxicology

Hydrofluoric Acid Related Injuries and Illness for First Responders

8/10/2021 Jett MacPherson, MSII
Emergency physicians, tactical medical providers, and other first responders are tasked with taking care of those who become injured or ill in mass gatherings that turn violent. Hydrofluoric acid expo