Browsing: Toxicology

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Toxicology , COVID-19

The Toxicology of COVID

4/10/2022 Michael Keenan, MD , Vincent Calleo, MD
Emergency physicians have watched with excitement the rapid development of COVID-19 vaccines. However, while we were watching the rapid scientific development, there was a concurrent wave of misguided
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Toxicology

Fomepizole for Acetaminophen Toxicity: A Novel Use for a Classic Antidote

12/12/2021 Shelby Randall, DO , Nicholas Titelbaum, MD , Alexa Peterson, DO, MS , Katelynn Baska, DO , Nicole Ovregaard, MPH, CPH
Acetaminophen toxicity is one of the most common causes of liver toxicity in the United States. New data reveals that fomepizole may be hepatoprotective in high dose acetaminophen toxicity when review
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Hematology , Pain Management , Toxicology

A Real Pain in the Mouth: Acquired Methemoglobinemia

12/12/2021 Emily Wolery, MD , Cynthia Oliva, MD , K.T. Dyer, MD
Acquired methemoglobinemia, a pathologic condition due to elevated quantities of methemoglobin in the blood, is an infrequent presentation in a healthy adult patient. This case illustrates the risk as
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Toxicology

Case of Doxepin Overdose

10/7/2021 Massud Atta, MD , Sanam Patel, MD , Jon Shivdat, DO , Pete Stueve, DO
Doxepin is a tricyclic antidepressant (TCA) that was primarily approved for depression but has also been approved by the Food and Drug Administration (FDA) to treat insomnia and anxiety. Do you know h
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Toxicology , Dermatology

Drug-Induced Erythema Multiforme

10/7/2021 Amna M. Farshori, DO , Daniel J. Schroder, DO
Erythema multiforme is an acute skin disorder. While most cases are the result of an infection, the condition can also result from autoimmune disorders, malignancy, and drug use.
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EMS , Disaster Medicine , Toxicology

Hydrofluoric Acid Related Injuries and Illness for First Responders

8/10/2021 Jett MacPherson, MSII
Emergency physicians, tactical medical providers, and other first responders are tasked with taking care of those who become injured or ill in mass gatherings that turn violent. Hydrofluoric acid expo
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Toxicology

Physostigmine for Severe Antimuscarinic Overdose: Pushing Back Against the Stigma

8/10/2021 Sahar Rammaha , Larry B. Mellick, MD, FACEP
Physostigmine has long been recognized as an antidote to reverse antimuscarinic delirium. However, its effectiveness, safety profile, and dosing have been disputed in recent years. But does this medic
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Trauma , Toxicology

Compartment Syndrome Secondary to Cocaine-Induced Rhabdomyolysis

8/10/2021 Kyle Parker, MD , Leslie Rea, MD , Anjeza Cipi, MD
Although substance-induced rhabdomyolysis has been widely reported, the progression to compartment syndrome is not frequently encountered and usually of multifactorial etiology. Rapid recognition of t
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Cardiology , Endocrinology , Toxicology

Euglycemic DKA and Hyponatremia Caused by a Commonly Prescribed Diabetic Medication

8/10/2021 Aaron Tiffee, MD, FACEP , Daniel Stout, MD , Taylor Curry
SGLT-2 inhibits can cause massive osmotic diuresis and intravascular volume depletion. The body’s appropriate response to this is production of antidiuretic hormone, an excess of which is capable of c
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Cardiology , Nephrology , Toxicology

BRASH Syndrome: A Vicious Cycle

8/10/2021 Emily Newton , Gabrielle Ransford, MD , Anjeza Cipi, MD
BRASH syndrome is an uncommon but often fatal condition in which an acute renal injury initiates a vicious cycle of bradycardia, hyperkalemia, hypotension and worsening renal failure in patients who t