Browsing: Toxicology

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Critical Care Alert , Critical Care , Airway , Toxicology

Critical Care Alert: Effect of Noninvasive Airway Management of Comatose Patients with Acute Poisoning: A Randomized Clinical Trial

2/22/2024 Alex Lucas, MD , Christian Kasianko, MD , Dustin Slagle, MD
How reliable is the old adage, "GCS less than 8, intubate"? A randomized trial examines the effect of intubation vs. noninvasive airway management for poisoned patients with GCS less than 8.
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Toxicology , Cardiology

ECMO…The Ultimate Antidote?

1/15/2024 Mason Jackson, MD , Lindsay Davis, DO, MPH, NRP , Brittany (Ladson) Garza, DO
There is no shortage of literature supporting the role of ECMO in acute coronary syndrome, sepsis, acute respiratory distress syndrome, cardiac arrest, pulmonary embolism, traumatic pulmonary contusio
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Neurology , Nephrology , Toxicology

Valacyclovir-Associated Neurotoxicity in End-Stage Renal Disease

1/15/2024 Chad Barnhart, MD, EMT-P , Matthew Ball, MD , Michael B. Holbrook, MD
Valacyclovir-associated neurotoxicity (VAN) is a relatively rare phenomenon. This case report details a unique presentation of VAN in a hemodialysis-dependent patient. It underscores the importance of
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Toxicology

The Dangers of Delta-8

9/15/2023 Brittany (Ladson) Garza, DO
Marijuana, THC (tetrahydrocannabinol), and CBD (cannabidiol) products are becoming increasingly popularized and legalized in our society. With the proliferation of these products’ use also comes accid
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Toxicology , Pediatric EM , Wilderness Medicine

The Teeny Tiny Mighty: A Case of Pediatric Envenomation With the Western Pygmy Rattlesnake

8/1/2023 Mounir Contreras, MD , Daniel Rivera, MD , Sing-Yi Feng, MD, FACMT
Western pygmy rattlesnake envenomations are a rare occurrence but should not be underestimated, as they cause significant morbidity. FabAV, also known as CroFab® (generic: crotalidae polyvalent immune
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Dermatology , Hematology , Oncology , Toxicology

Warfarin-Induced Skin Necrosis: Not Your Typical Rash

4/15/2023 Brandon Murdock, MD , Chung-ting J. Kou , Paul A. Gonzales , David M. Crawford
Warfarin-induced skin necrosis (WISN) is a rare condition thought to be due to microvascular thrombosis and ischemia and is commonly related to protein C deficiency. Recognition of WISN is critical to
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Toxicology

I Ordered the Urine Drug Screen, Now What? An Overview on Testing, Interference, and Utility of UDS in the ED

4/15/2023 Mason Jackson, MD , Lindsay Davis, DO, MPH, NRP , Alexa Peterson, DO, MS
The urine drug screen is a widely used, but imperfect, diagnostic test. Because of its potential flaws, it should not be used out of context or in isolation, but it remains a valuable test in the tool
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Toxicology

Top Gun Toxicity: Military-Grade Hydrocarbon Exposure Management in the ED

1/30/2023 E. Mason Jackson, MD , Michael Troise, MD
The ramifications of military fuel leaks extend beyond environmental disasters to acute exposures/ingestions and chronic toxicity. With more than 450 military bases in the United States, many of which
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Toxicology , Nephrology

A Case of Intentional Salt Ingestion Leading to Life-Threatening Hypernatremia

1/30/2023 Christopher M Mashiak, MD , Johndavid M Storn, MD , Jennifer V Pope, MD
Acute salt ingestion should be rapidly corrected to reduce serum osmolality. This can be done with an infusion of hypotonic solutions, such as 5% dextrose in water (D5W), with a goal reduction of 1 mm
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Toxicology

Buprenorphine Induction: Where We Are and Where We’re Headed

10/10/2022 Lance Shaull, MD
Buprenorphine has been shown to be a safe and effective medication in multiple settings with extensive research on both unobserved induction and physician-observed induction. Emerging evidence suggest