Toxicology

Physostigmine for Severe Antimuscarinic Overdose: Pushing Back Against the Stigma

8/10/2021 Sahar Rammaha , Larry B. Mellick, MD, FACEP

Physostigmine has long been recognized as an antidote to reverse antimuscarinic delirium. However, its effectiveness, safety profile, and dosing have been disputed in recent years. But does this medic

48-4 Compartment Syndrome Figures 1-4.png

Trauma , Toxicology

Compartment Syndrome Secondary to Cocaine-Induced Rhabdomyolysis

8/10/2021 Kyle Parker, MD , Leslie Rea, MD , Anjeza Cipi, MD

Although substance-induced rhabdomyolysis has been widely reported, the progression to compartment syndrome is not frequently encountered and usually of multifactorial etiology. Rapid recognition of t

Cardiology , Endocrinology , Toxicology

Euglycemic DKA and Hyponatremia Caused by a Commonly Prescribed Diabetic Medication

8/10/2021 Aaron Tiffee, MD, FACEP , Daniel Stout, MD , Taylor Curry

SGLT-2 inhibits can cause massive osmotic diuresis and intravascular volume depletion. The body’s appropriate response to this is production of antidiuretic hormone, an excess of which is capable of c

Cardiology , Nephrology , Toxicology

BRASH Syndrome: A Vicious Cycle

8/10/2021 Emily Newton , Gabrielle Ransford, MD , Anjeza Cipi, MD

BRASH syndrome is an uncommon but often fatal condition in which an acute renal injury initiates a vicious cycle of bradycardia, hyperkalemia, hypotension and worsening renal failure in patients who t

Wilderness Medicine , Toxicology

Managing Envenomation: Be Prepared for Summertime Exposure

6/11/2021 Luke He, MD , John Michael Sherman, MD , Christopher Rajan, DO , Geoff Comp, DO, FAWM

Post-pandemic vacations are picking up steam - and outdoor getaways remain popular. Are you ready to handle bites, stings, and other envenomations?

Toxicology

Caustic Ingestions: Feel the Burn

4/8/2021 James Wang, MD , Neha Sehgal, DO , Susan Watts, PhD

Caustic ingestions cause either coagulative (acidic substance) or liquefactive (alkaline substance) necrosis. Management and treatment include observation, labs, imaging, endoscopy, and may require mo

Toxicology , Hematology

Bleeding Risk after NSAID Use

4/8/2021 Colton Beck , MAJ John Kiel, DO, MPH, CAQ-SM

NSAIDs are the most commonly used class of drugs in the world. They possess analgesic, antipyretic, and anti-inflammatory properties. Its GI side effects are most apparent and well-documented and can

48-2 Hemopericardium - cxr-supine-ap Fig 1.jpg

Cardiology , Hematology , Toxicology

Sudden Post-Coital Hemopericardium with Cardiac Tamponade on Apixaban

4/8/2021 Hardeep Hunjan, DO , Tiffany Anaebere, MD

Direct oral anticoagulants (DOACs) have become the preferred anticoagulant medication for patients with nonvalvular atrial fibrillation, deep vein thrombosis, and pulmonary embolism. However, recent c

Toxicology , Medications

Strong Enough for a Giraffe, But Made for a Human: Alpha 2-adrenergic Agonist Overdose

10/9/2020 Scott H. Witt, MD , Erich Burton, DO

Recognizing alpha 2-agonist overdose and distinguishing it from other etiologies of bradycardia and hypotension is critically important.

Cardiology , Toxicology , Medications

Acute Hyperkalemia Masking Flecainide and Metoprolol Toxicity

10/9/2020 Matthew Baltz, MD , Jeremy Berberian, MD

Antidysrhythmic drugs are broadly categorized into Vaughan-Williams classifications, and their effects should be carefully noted.

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