Browsing: Critical Care Alert

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Critical Care , Critical Care Alert , COVID-19

Critical Care Alert: Effect of Hydrocortisone on Mortality or Respiratory Support Among Critically Ill with COVID-19 Patients

10/8/2020 Oswald Reid, Jr., MD , Sean M. Hickey, MD
While the treatment for SARS-CoV-2 continues to evolve, the emergency department remains a primary place for early medical intervention. There is growing evidence to support that initiating steroids w
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Critical Care , Critical Care Alert , COVID-19

Critical Care Alert: Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19. The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial

9/21/2020 Brian Sumner, MD , Sean M. Hickey, MD
A complex trial meant to determine whether hydrocortisone can improve outcomes for patients with severe COVID-19 was stopped early - but still shows promise for the course.
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Critical Care , Critical Care Alert , COVID-19

Critical Care Alert: Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients with Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial

9/21/2020 Taylor Miller, MD , Sean M. Hickey, MD
The CoDEX trial was conducted to identify the effect of dexamethasone on ventilator-free days in patients with COVID-19 associated ARDS.
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Critical Care , Critical Care Alert , COVID-19

Critical Care Alert: Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis

9/21/2020 Brian Sumner, MD , Sean M. Hickey, MD
With no clear consensus on the use of steroids in critically ill sepsis patients, a recent meta-analysis studies the 28-day mortality in critically ill COVID-19 patients when corticosteroids are admin
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Critical Care , Critical Care Alert

Critical Care Alert: Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock - The ACTS Randomized Clinical Trial

9/3/2020 Brian Sumner, MD , Sean M. Hickey, MD
This study sheds more light on how the administration of ascorbic acid, corticosteroids, and thiamine might affect the rates of organ injury in patients suffering septic shock. The takeaway? It's not
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Critical Care , Critical Care Alert

Critical Care Alert: Etomidate Use Is Associated with Less Hypotension Than Ketamine for Emergency Department Sepsis Intubations: A NEAR Cohort Study

8/26/2020 Brian Sumner, MD , Sean M. Hickey, MD
Intubating the critically ill septic patient is a high-risk procedure. We examine an observational study that reported higher levels of procedural hypotension with the use of ketamine when compared to
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Critical Care , Critical Care Alert

Critical Care Alert: Effects of Dexamethasone in Hospitalized Patients with COVID-19 - Preliminary Report

6/26/2020 Taylor Miller, MD , Sean M. Hickey, MD , Trevor R. Pour, MD
As much of the U.S. experiences a resurgence of COVID-19 cases heading into the height of summer, research continues at a brisk pace. Can dexamethasone - a relatively inexpensive, commonly prescribed
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Critical Care , Critical Care Alert

Critical Care Alert: Preliminary Report on Remdesivir for the Treatment of COVID-19

6/1/2020 Taylor Miller, MD , Sean M. Hickey, MD
The Adaptive COVID-19 Treatment Trial (ACTT), while controversial, is the first major trial to suggest benefit from remdesivir for hospitalized COVID-19 patients. Unfortunately, study results don't sh
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Critical Care , Critical Care Alert

Critical Care Alert: Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock

5/26/2020 Taylor Miller, MD , Sean M. Hickey, MD
In the quest to conquer sepsis, a new randomized controlled trial has tested hydrocortisone, vitamin C, and thiamine as a treatment.
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Critical Care , Critical Care Alert

Critical Care Alert: Dexamethasone Treatment for ARDS

5/7/2020 Taylor Miller, MD , Sean M. Hickey, MD
The first RCT studying the use of dexamethasone in ARDS shows promise for the emergency medicine setting.