Browsing: Critical Care

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Critical Care , Critical Care Alert

Critical Care Alert: Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock

5/26/2020 Taylor Miller, MD , Sean M. Hickey, MD
In the quest to conquer sepsis, a new randomized controlled trial has tested hydrocortisone, vitamin C, and thiamine as a treatment.
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Critical Care , Critical Care Alert

Critical Care Alert: Dexamethasone Treatment for ARDS

5/7/2020 Taylor Miller, MD , Sean M. Hickey, MD
The first RCT studying the use of dexamethasone in ARDS shows promise for the emergency medicine setting.
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Critical Care

Pneumomediastinum Secondary to Medication-Induced Esophageal Microperforation

4/22/2020 Anil Bhagavath, MD , Robert L. Gekle, MD, FACEP
Here's a case you don't see every day: a single dose of over-the-counter cold medicine led to an esophageal perforation, which then resulted in pneumomediastinum.
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Critical Care , Critical Care Alert

Critical Care Alert: Prevention of Early Ventilator-Associated Pneumonia After Cardiac Arrest

4/21/2020 Sarah Ring, MD , Sean M. Hickey, MD
Can prophylactic antibiotics affect the incidence of ventilator-associated pneumonia following out-of-hospital cardiac arrest?
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Critical Care , Critical Care Alert

Critical Care Alert: Hydrocortisone, Thiamine, and Vitamin C in Septic Shock

2/17/2020 Greg Felock, MD , Sean M. Hickey, MD
The VITAMINS Trial looked at the role of vitamin C, thiamine, and hydrocortisone in saving patients with septic shock. It's the first randomized controlled trial focused on whether vitamins can provid
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Critical Care , Critical Care Alert

Critical Care Alert: Conservative Oxygen Therapy in Mechanically Ventilated Patients - the ICU-ROX Study

2/10/2020 Melissa Villars, MD, MPH , Sean M. Hickey, MD
The ICU-ROX study, designed as the largest RCT of mechanically ventilated ICU patients, investigates whether conservative oxygen therapy could reduce mortality. Are the results enough to tip the scale
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Critical Care , Critical Care Alert

Critical Care Alert: Epinephrine for Out-of-Hospital Cardiac Arrest

1/10/2020 Melissa Villars, MD, MPH , Sean M. Hickey, MD
This review article was trying to take another look at the impact of epinephrine, especially its impact on meaningful neurologic survival, to see if the debates launched by the PARAMEDIC-2 trial were
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Critical Care , Critical Care Alert

Critical Care Alert: Reviewing the Evidence for CITRIS-ALI Study

1/3/2020 Melissa Villars, MD, MPH , Sean M. Hickey, MD
Can vitamin C benefit patients with sepsis-related ARDS? Take a look at the evidence from the CITRIS-ALI study before you take a stance in this ongoing debate.
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Critical Care , Critical Care Alert

Critical Care Alert: Medications for Status Epilepticus - The ESETT Trial

12/23/2019 Melissa Villars, MD, MPH , Sean M. Hickey, MD
Sometimes a clinical trial shows no statistical differences yet can help to illuminate best practices. Count the ESETT Trial as one of them.
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Critical Care , Critical Care Alert

Critical Care Alert: Targeted Temperature Management for Cardiac Arrest with Non-shockable Rhythm - The HYPERION Trial

12/19/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD
Moderate therapeutic hypothermia could be another tool in treating cardiac arrest patients. But how much should a patient be cooled? The HYPERION Trial doesn't resolve that debate.