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The ECLS-SHOCK Trial investigated whether extracorporeal life support would benefit patients suffering acute myocardial infarction complicated by cardiogenic shock. Is VA-ECMO always the answer?
What role does amiodarone or lidocaine play in achieving a good outcome for shockable refractory out-of-hospital cardiac arrest? This Critical Care Alert looks at a follow-up to the ALPS study.
This Critical Care Alert examines a study of targeted mild hypercapnia versus normocapnia for patients who achieved ROSC after out-of-hospital cardiac arrest.
In this underpowered RCT, no evidence was found that TXA limits HE nor that it improves clinical outcomes by 90 days in NOAC-associated ICH. That being said, there were no major safety concerns noted
More evidence is stacking up in favor of video laryngoscopy. The DEVICE Trial shows that when intubating critically ill patients in the ED or ICU, consider using video over direct laryngoscopy to impr
The EXTUB-OBESE study showed a decrease in extubation failure rates when extubating to non-invasive ventilation for obese patients vs. standard oxygen therapy.
The PATCH-Trauma Trial confirms short-term benefits of tranexamic acid (TXA) for prehospital treatment of the bleeding trauma patient, despite no evidence of long-term functional benefits.
Can methylene blue play a role in treating your patient with septic shock? This randomized control trial shows earlier vasopressor discontinuation and shorter ICU and hospital lengths of stay - but no
While it didn’t improve survival to hospital discharge or neurologic recovery vs the current standard of care, the sudden death CT (SDCT) protocol significantly improved the time and diagnostic abilit
In a recent study, fludrocortisone added to hydrocortisone was associated with increased hospital survival, shorter hospital lengths of stay, and decreased vasopressor duration when compared to hydroc