Acetaminophen Overdose
Acetaminophen Overdose
Sept. 15, 2024
Acetaminophen overdose will likely show up in your exam bay (and more than likely on your boards). A recent EM consensus statement takes a fresh look at management, so EMRA*Cast host Kyle Duke, MD, breaks it down with EMRA Toxicology Committee Chair Mason Jackson, MD.
Host
Kyle Duke, MD
Prisma Health - Greenville
EMRA*Cast Episodes
OVERVIEW
SUMMARY
Acetaminophen is widely available over the counter in the United States, increasing the risk of overdose (both acute and chronic). Several factors contribute to the complexity of managing this tricky condition in the emergency department, but until recently, there has been no true standardized approach. Guidance issued in 2023 aims to establish a helpful framework for managing acetaminophen overdose.
RESOURCES
- Dart RC, Mullins ME, Matoushek T. Management of acetaminophen poisoning in the US and Canada. JAMA Netw Open. 2023;6(8):e2327739.
- The Poison Lab. Ryan Feldman, PharmD, DABAT. Episode 23: Acetaminophen poisoning management: US & Canada consensus statement with co-author Dr. Richard Dart, MD, PhD. Aug. 18, 2023.
- Randall S, Titelbaum N, Peterson A, Baska K, Ovregaard N. Fomepizole for acetaminophen toxicity: a novel use for a classic antidote. EM Resident. 2022;48(6):12-13.
- EMRA and ACMT Medical Toxicology Guide. Katz KD, O’Connor A, eds. 2022. [Also accessed through MobilEM]
