Critical Care , Critical Care Alert

Critical Care Alert: Epinephrine for Out-of-Hospital Cardiac Arrest

1/10/2020 Melissa Villars, MD, MPH , Sean M. Hickey, MD

This review article was trying to take another look at the impact of epinephrine, especially its impact on meaningful neurologic survival, to see if the debates launched by the PARAMEDIC-2 trial were

Critical Care , Critical Care Alert

Critical Care Alert: Reviewing the Evidence for CITRIS-ALI Study

1/3/2020 Melissa Villars, MD, MPH , Sean M. Hickey, MD

Can vitamin C benefit patients with sepsis-related ARDS? Take a look at the evidence from the CITRIS-ALI study before you take a stance in this ongoing debate.

Critical Care , Critical Care Alert

Critical Care Alert: Medications for Status Epilepticus - The ESETT Trial

12/23/2019 Melissa Villars, MD, MPH , Sean M. Hickey, MD

Sometimes a clinical trial shows no statistical differences yet can help to illuminate best practices. Count the ESETT Trial as one of them.

Critical Care , Critical Care Alert

Critical Care Alert: Targeted Temperature Management for Cardiac Arrest with Non-shockable Rhythm - The HYPERION Trial

12/19/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD

Moderate therapeutic hypothermia could be another tool in treating cardiac arrest patients. But how much should a patient be cooled? The HYPERION Trial doesn't resolve that debate.

Critical Care , Critical Care Alert

Critical Care Alert: CRASH-3 Review of TXA for TBI

12/16/2019 Ryan Lee, MD , Raymond Green, DO, FACS , Michael Perza, PharmD, BCPS

Released in October 2019, CRASH-3 is the latest trial exploring the benefits of tranexamic acid, this time in traumatic brain injury. The bottom line: TXA hasn't been shown to reduce mortality.

Critical Care , Critical Care Alert

Critical Care Alert: Reviewing the Evidence for SEP-1

10/9/2019 Omid Manoochehri, MD , Sean M. Hickey, MD

The SEP-1 core measure instituted by CMS has been hotly debated. A new review of literature shows a lack of high-quality evidence to back up the specificity required in the sepsis bundle.

Critical Care , Critical Care Alert

Critical Care Alert: The Restrictive IV Fluid Trial in Severe Sepsis and Septic Shock (RIFTS)

8/12/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD

Fluid resuscitation guidelines for severe sepsis and septic shock presently address only the initial phase of resuscitation. The RIFTS trial examines the efficacy of a restrictive IV fluid resuscitati

Critical Care , Critical Care Alert

Critical Care Alert: Re-evaluation of Systemic Early Neuromuscular Blockade: The ROSE Trial

7/16/2019 Jonathan Pickos, DO , Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD

Does early neuromuscular blockade accompanied by heavy sedation in ARDS cases improve all-cause in-hospital mortality rates? The ROSE trial investigates.

Critical Care , Critical Care Alert

Critical Care Alert: Measuring Lactate vs. Capillary Refill in Guiding Resuscitation in Shock: Is there a difference?

6/11/2019 Bryan Beattie, MD , Sean M. Hickey, MD

When trying to resuscitate patients with septic shock, which offers better guidance for intervention: measuring capillary refill or trending lactate levels? The Andromeda SHOCK trial studied patients

Critical Care , Critical Care Alert

Critical Care Alert: Closed Chest Compressions in Traumatic Cardiac Arrest

5/18/2019 Sean M. Hickey, MD , Bryan Beattie, MD

The study authors sought to examine the effect of closed chest compressions on cardiac arrest due to hemorrhagic shock versus whole blood resuscitation.

Browsing: Critical Care Alert

Critical Care Alert: Epinephrine for Out-of-Hospital Cardiac Arrest

Critical Care Alert: Reviewing the Evidence for CITRIS-ALI Study

Critical Care Alert: Medications for Status Epilepticus - The ESETT Trial

Critical Care Alert: Targeted Temperature Management for Cardiac Arrest with Non-shockable Rhythm - The HYPERION Trial

Critical Care Alert: CRASH-3 Review of TXA for TBI

Critical Care Alert: Reviewing the Evidence for SEP-1

Critical Care Alert: The Restrictive IV Fluid Trial in Severe Sepsis and Septic Shock (RIFTS)

Critical Care Alert: Re-evaluation of Systemic Early Neuromuscular Blockade: The ROSE Trial

Critical Care Alert: Measuring Lactate vs. Capillary Refill in Guiding Resuscitation in Shock: Is there a difference?

Critical Care Alert: Closed Chest Compressions in Traumatic Cardiac Arrest

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Sexual Assault in Critical Care

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